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M Shibasaki Selected Research

2- (4- bromophenyl)- 6- methyl- N- (2- (1- oxidopyridin- 3- yl)ethyl)pyrimidin- 4- amine

1/2011The role of small molecule GPR119 agonist, AS1535907, in glucose-stimulated insulin secretion and pancreatic β-cell function.

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M Shibasaki Research Topics

Disease

10Asthma (Bronchial Asthma)
05/2006 - 06/2000
4Type 2 Diabetes Mellitus (MODY)
01/2011 - 03/2000
4Body Weight (Weight, Body)
12/2008 - 03/2000
4Insulin Resistance
08/2006 - 04/2002
3Inflammation (Inflammations)
10/2009 - 11/2001
2Hypersensitivity (Allergy)
10/2009 - 06/2000
1Substance-Related Disorders (Drug Abuse)
03/2011
1Hemorrhage
10/2010
1Hypovolemia
11/2009
1Respiratory Tract Diseases (Respiratory Tract Disease)
10/2009
1Seizures (Absence Seizure)
02/2008
1Human Influenza (Influenza)
02/2008
1Venous Thromboembolism
04/2007
1Hypertriglyceridemia
08/2006
1Metabolic Syndrome (Dysmetabolic Syndrome X)
08/2006
1Glucose Intolerance
10/2004
1Infections
02/2004
1Hyperalgesia
01/2004
1Neuralgia (Stump Neuralgia)
01/2004
1Pain (Aches)
01/2004
1Atopic Dermatitis (Atopic Eczema)
10/2003
1Netherton Syndrome
10/2003
1Hyperinsulinism (Hyperinsulinemia)
09/2003
1Rhinitis
11/2001
1Ischemia
10/2001
1Cardiomegaly (Heart Hypertrophy)
05/2001
1Heart Failure
05/2001
1Necrosis
11/2000
1Spasm (Spasms)
08/2000
1Ventricular Fibrillation
08/2000
1Schizophrenia (Dementia Praecox)
04/2000
1Hyperglycemia
03/2000

Drug/Important Bio-Agent (IBA)

7Immunoglobulin E (IgE)IBA
10/2009 - 06/2000
5Insulin (Novolin)FDA Link
01/2011 - 03/2000
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2004 - 11/2000
3Glucose (Dextrose)FDA LinkGeneric
01/2011 - 10/2004
3AllergensIBA
10/2009 - 06/2000
2Hypoglycemic Agents (Hypoglycemics)IBA
12/2008 - 03/2000
2DNA (Deoxyribonucleic Acid)IBA
05/2006 - 02/2004
22,4-thiazolidinedione (thiazolidinedione)IBA
10/2004 - 03/2000
2Pioglitazone (Actos)FDA Link
09/2003 - 03/2000
2Interleukin-12 (IL 12)IBA
11/2001 - 06/2000
2Interleukin-4 (Interleukin 4)IBA
11/2001 - 11/2000
2EnalaprilFDA LinkGeneric
05/2001 - 02/2000
2Angiotensin IIIBA
05/2001 - 02/2000
2YM358IBA
05/2001 - 02/2000
1Pharmaceutical PreparationsIBA
03/2011
12- (4- bromophenyl)- 6- methyl- N- (2- (1- oxidopyridin- 3- yl)ethyl)pyrimidin- 4- amineIBA
01/2011
1CD55 Antigens (Decay Accelerating Factor)IBA
10/2009
1Niacinamide (Nicotinamide)FDA LinkGeneric
12/2008
1Blood Glucose (Blood Sugar)IBA
12/2008
1Streptozocin (Streptozotocin)FDA Link
12/2008
1Glutamic Acid (Glutamate)FDA Link
02/2008
1Oseltamivir (Tamiflu)FDA Link
02/2008
1Antiviral Agents (Antivirals)IBA
02/2008
1CD40 Ligand (CD40L)IBA
04/2007
1Thromboplastin (Tissue Factor)IBA
04/2007
1Lipoprotein Lipase (Diacylglycerol Lipase)IBA
08/2006
1DisintegrinsIBA
05/2006
1Metalloproteases (Metalloproteinases)IBA
05/2006
1ResistinIBA
10/2004
1EndotoxinsIBA
02/2004
1Toll-Like Receptors (Toll-Like Receptor)IBA
02/2004
1Ro 32-0432IBA
01/2004
1Morphine (MS Contin)FDA LinkGeneric
01/2004
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
01/2004
1Protein Kinase CIBA
01/2004
1Serine Peptidase Inhibitor Kazal-Type 5IBA
10/2003
1Proteins (Proteins, Gene)FDA Link
09/2003
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
09/2003
1Immunoglobulins (Immunoglobulin)IBA
03/2003
1MucinsIBA
03/2003
1prostaglandin R2 D-isomerase (prostaglandin D2 synthase)IBA
01/2002
1ProstaglandinsIBA
01/2002
1Prostaglandin D2IBA
01/2002
1prostaglandin D2 receptorIBA
01/2002
1OvalbuminIBA
01/2002
1Interleukin-13IBA
11/2001
1CytokinesIBA
11/2001
1Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric
10/2001
1Phenylephrine (Neo-Synephrine)FDA LinkGeneric
10/2001
1Cytidine DeaminaseIBA
09/2001
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
05/2001
1YM 126414IBA
12/2000
1paraform (paraformaldehyde)IBA
11/2000
1Interferon Regulatory Factor-1 (Interferon Regulatory Factor 1)IBA
11/2000
1Ergonovine (Ergometrine)IBA
08/2000
1Prednisolone (Predate)FDA LinkGeneric
08/2000
1Nifedipine (Adalat)FDA LinkGeneric
08/2000
1IsosorbideFDA Link
08/2000
1AntibodiesIBA
06/2000
1bromperidol (Impromen)IBA
04/2000
1PPAR gammaIBA
03/2000

Therapy/Procedure

2Lower Body Negative Pressure
10/2010 - 11/2009
1Orthopedic Procedures
04/2007
1Hip Replacement Arthroplasty (Total Hip Replacement)
04/2007
1Ligation
01/2004
1Transplantation
09/2003
1Oral Administration
05/2001
1Drug Therapy (Chemotherapy)
04/2000